Actifuse Microgranules key features:
Silicate substitution changes the surface charge of the material attracting more of the proteins that bind osteoblasts (bone-forming cells). This accelerates bone formation
Optimized structure with interconnected porosity encourages and supports rapid bone formation
Actifuse resorption is cell mediated and avoids a biological race between graft dissolution and new bone formation. This minimises the risk of a foreign body response to particulate debris observed with some synthetic materials
In vitro and in vivo data demonstrate that Actifuse enhances each of the key steps in bone formation and can produce more high quality bone, more rapidly than other synthetic materials
Actifuse. More bone, less time
1-2mm granules for small graft areas
Cohesive graft in 20 minutes when mixed with blood or bone marrow aspirate.
The unique granular structure of Actifuse, when combined with localized blood or in combination with blood marrow aspirate, in a ration of 1-1.5:1 (blood/BMA to Actifuse) allows for optimal handling and placement characteristics.
Order information:
| Product Code | Granule Size | Pack Size |
| 506005078041 | 1-2mm | 2.5ml |
| 506005078042 | 1-2mm | 5ml |
| 506005078043 | 1-2mm | 10ml |
Indications for Use: Europe and Australia
Bone graft substitutes are intended to be used in place of corticocancellous, or cancellous allograft or autograft bone. The mechanical environment for such uses experience either low load requirements or compression. Typical surgical applications for bone graft substitutes are:
- Small void filling, e.g. after removal of a small bone tumour or following bone fracture reduction or in osteotomies and plastic surgery
- Spinal fusion, where a cage or screw fixation device is used to relieve the graft site from physiological loads
It is not intended to be used in place of cortical strut allograft bone where high tensile, torsion and/or bending strength are required. The products are used by orthopaedic surgeons in place of allograft bone (bone from humans stored in bone banks).
